Visualizing Space Usage Patterns in a Health Sciences Library

The Tompkins-McCaw Library for the Health Sciences collected user location information to analyze public space usage. The data were used to create heat map representations of average occupancy rates at specific locations within the building

The Power of Closing Time: Using Library Occupancy Data to Inform Operational Changes

Objectives: To use hourly building occupancy data over the period of 2012-2014 to determine the effect of changes to library hours of operation on building occupancy near and in the hours leading up to closing time. Methods: Data were collected using an automated gate count system at the primary entrance to the library. The system tracked the occupancy of the building by comparing the number of entrances and exits hourly each day. Incremental changes to the library’s hours of operation occurred in the same time period for the years 2012-2014. This time period will be compared year-to-year. We will test whether changes in closing time have a significant effect on mean occupancy rates during each of the three hours leading up to closing. Based on a previous study which examined a smaller, six-week period between 2012-2014, we expect to find that as closing time is extended, building occupancy in the hours preceding closing time increases despite a decrease in occupancy at closing. Results: Mean occupancy during the hour before closing time did not change when closing time was extended from 9 PM to 10PM. When closing time was extended to 12 AM, mean occupancy during the hour before closing decreased. Mean occupancy during the hour ending at 9 PM increased when closing time was extended from 9 PM to 10 PM. Mean occupancy during the hour ending at 10 PM increased when closing time was extended from 10 PM to 12 AM. We plan to also include data from the ongoing Spring semester in the final results. Conclusions: Occupancy near closing decreased as closing time became later. While occupancy near closing decreased somewhat, occupancy earlier in the evening increased as library hours were extended. The benefits of increased library occupancy appear to justify sustaining extended operating hours

Seasonal Variation of Physical Activity in Community-Living vs. Residential-Dwelling Older Adults

Background and Purpose: Although physical activity (PA) is important for all ages including older adults, participation may be influenced by weather variation and access to programming. Our primary aim was determine if PA participation is influenced by season and place of residence. A secondary aim was to compare objective and subjective measure of PA participation. Methods: Participants included older individuals (age>65) living in a residential retirement community (RR) with access to an on-site fitness facility (n=7) and additional volunteers (n=9) who lived at home and traveled to exercise at a nonresidential community (NR) activities center Accelerometers were used to measure daily PA during the summer and again during the winter. Results: PA for the NR group was higher in the summer (268.4�73.7 min vs. RR=186.8�68.0, p=0.039), but not in the winter (NR=261.8�92.6 min, RR=182.0�72.5, p=0.082). No within-group change in PA was noted from summer to winter for either group (p>0.05). The correlation between subjective and objective measures of PA was low (r=.262). Conclusion: Access to appropriate facilities and programming serves to help older individuals maintain PA levels despite seasonal weather variations. The low correlation between objective and subjective measures suggest a need to re-evaluate methods of tracking PA participation by older adults

ENVIRONMENTAL AND ECONOMIC IMPACTS OF SOIL EROSION AND FERTILITY MINING IN NORTHERN TANZANIA

This paper develops a soil conservation model that is relevant to smallholder farmers who apply little or no fertilizer. Empirical results drawn from northern Tanzania imply that, ignoring fertility mining problem in model specification leads to overestimation of profits for farms that apply little or no fertilizer. The model also shows that, the impact of output price on soil conservation efforts depends on the curvature of the soil erosion function.Soil erosion, Fertility mining, Soil conservation, Price policy, Soil erosion function, Sub-Saharan Africa, Tanzania., Environmental Economics and Policy, Land Economics/Use,

RAMSWay Safe Path

RAMSWay promotes safety for students, faculty, staff, and visitors with a series of safe walkways connecting key locations, such as classroom buildings, gyms, libraries, residence halls, and parking decks, on Virginia Commonwealth University’s sprawling urban campus. RAMSWay paths are designed to be consistent with the theoretical framework referred to as CPTED (Crime Prevention Through Environmental Design). CPTED suggests that altering the physical design of communities or areas in which people congregate can deter criminal activity. CPTED-compliant landscaping and lighting, security features (e.g., cameras, ERTs phones), and increased police presence on the paths promote the sense of safety. Further, increased foot traffic provides safety in numbers, consistent with VCU’s current Bystander Intervention initiative. VCU branded RAMSWay aluminum signs will designate walkways on both the Monroe Park and MCV campuses, showing pedestrians a preferred route. When traveling on RAMSWay, members of the VCU community will have more opportunities to interface with VCU Police, pass by ERTs phones, and share the route with fellow students, faculty, and staff. By using the path, we all help do our part to promote safety on our campus. Existing organizations and communication platforms, such as VCU University Relations, Student Government Association, VCU Mobile and LiveSafe, will promote the use of RAMSWay to the VCU community. RAMSWay will be executed in coordination with VCU Police and VCU Facilities

Genetic relationship between predisposition for binge alcohol consumption and blunted sensitivity to adverse effects of alcohol in mice

BACKGROUND: Initial sensitivity to ethanol (EtOH) and the capacity to develop acute functional tolerance (AFT) to its adverse effects may influence the amount of alcohol consumed and may also predict future alcohol use patterns. The current study assessed sensitivity and AFT to the ataxic and hypnotic effects of EtOH in the first replicate of mice (HDID-1) selectively bred for high blood EtOH concentrations (BECs) following limited access to EtOH in the Drinking in the Dark (DID) paradigm. METHODS: Naïve male and female HDID-1 and HS/Npt mice from the progenitor stock were evaluated in 3 separate experiments. In Experiments 1 and 2, EtOH-induced ataxia was assessed using the static dowel task. In Experiment 3, EtOH-induced hypnosis was assessed by using modified restraint tubes to measure the loss of righting reflex (LORR). RESULTS: HDID-1 mice exhibited reduced initial sensitivity to both EtOH-induced ataxia (p < 0.001) and hypnosis (p < 0.05) relative to HS/Npt mice. AFT was calculated by subtracting the BEC at loss of function from the BEC at recovery (Experiments 1 and 3) or by subtracting BEC at an initial recovery from the BEC at a second recovery following an additional alcohol dose (Experiment 2). The dowel test yielded no line differences in AFT, but HS/Npt mice developed slightly greater AFT to EtOH-induced LORR than HDID-1 (p < 0.05). CONCLUSIONS: These results suggest that HDID-1 mice exhibit aspects of blunted ataxic and hypnotic sensitivity to EtOH which may influence their high EtOH intake via DID, but do not display widely different development of AFT. These findings differ from previous findings with the high alcohol-preferring (HAP) selected mouse lines, suggesting that genetic predisposition for binge, versus other forms of excessive alcohol consumption, is associated with unique responses to EtOH-induced motor incoordination

Avoiding Irrational NeuroLaw Exuberance: A Plea for Neuromodesty

In a 2002 editorial published in The Economist, the following warning was given: Genetics may yet threaten privacy, kill autonomy, make society homogeneous and gut the concept of human nature. But neuroscience could do all of these things first. The genome was fully sequenced in 2001, and there has not been one resulting major advance in therapeutic medicine since. Thus, even in its most natural applied domain-medicine-genetics has not had the far-reaching consequences that were envisioned. The same has been true for various other sciences that were predicted to revolutionize the law, including behavioral psychology, sociology, psychodynamic psychology, and others. This will also be true of neuroscience, which is simply the newest science on the block. Neuroscience is not going to do the terrible things The Economist fears, at least not for the foreseeable future. Neuroscience has many things to say but not nearly as much as people would hope, especially in relation to law. At most, in the near to intermediate term, neuroscience may make modest contributions to legal policy and case adjudication. Nonetheless, there has been irrational exuberance about the potential contribution of neuroscience, an issue I have addressed previously and referred to as Brain Overclaim Syndrome. I first consider the law\u27s motivation and the motivation of some advocates to turn to science to solve the very hard normative problems that law addresses. Part III discusses the law\u27s psychology and its concepts of the person and responsibility. The next Part considers the general relation of neuroscience to law, which I characterize as the issue of translation. Part V canvasses various distractions that have bedeviled clear thinking about the relation of scientific, causal accounts of behavior to responsibility. The following Part examines the limits of neurolaw and Part VII considers why neurolaw does not pose a genuinely radical challenge to the law\u27s concepts of the person and responsibility. Part VIII makes a case for cautious optimism about the contribution neuroscience may make to law in the near and intermediate term. A brief conclusion follows..

Quantifying nitrous oxide emissions in the U.S. Midwest: a top‐down study using high resolution airborne in‐situ observations

The densely farmed U.S. Midwest is a prominent source of nitrous oxide (N2O) but top‐down and bottom‐up N2O emission estimates differ significantly. We quantify Midwest N2O emissions by combining observations from the Atmospheric Carbon and Transport‐America campaign with model simulations to scale the Emissions Database for Global Atmospheric Research (EDGAR). In October 2017 we scaled agricultural EDGAR v4.3.2 and v5.0 emissions by factors of 6.3 and 3.5, respectively, resulting in 0.42 nmol m−2 s−1 Midwest N2O emissions. In June/July 2019, a period when extreme flooding was occurring in the Midwest, agricultural scaling factors were 11.4 (v4.3.2) and 9.9 (v5.0), resulting in 1.06 nmol m−2 s−1 Midwest emissions. Uncertainties are on the order of 50 %. Agricultural emissions estimated with the process‐based model DayCent (Daily version of the CENTURY ecosystem model) were larger than in EDGAR but still substantially smaller than our estimates. The complexity of N2O emissions demands further studies to fully characterize Midwest emissions

Peer relations and emotion regulation of children with emotional and behavioural difficulties with and without a developmental disorder

Children with emotional and behavioural difficulties (EBD) and those who also have developmental disorders, such as attention deficit hyperactivity disorder (ADHD) or autism spectrum disorder (ASD), can experience the same adverse consequences in their peer interactions and relationships. This present study compared the emotion regulation and peer relationships of children aged 8-12 years (M = 9.86 years, SD = 1.49) with EBD (N = 33) and children with EBD plus a diagnosed developmental disorder (N = 28). Multivariate analysis of variance (MANOVA) with Bonferroni adjusted alpha levels revealed no significant main effect for emotion regulation according to EBD status. There was, however, a multivariate main effect for sex, with females presenting with higher levels of negative emotional intensity (e. g., frustration, anger, aggression) than males. A second MANOVA revealed no significant main effect for peer relationships according to EBD status and sex. Significant correlations revealed that the EBD-only group experienced greater adverse peer interactions than the EBD-plus-developmental disorder group. These findings are important for educators and researchers involved in the development and evaluation of prevention and intervention programms for children with EBD

Interactions between the adducin 2 gene and antihypertensive drug therapies in determining blood pressure in people with hypertension

<p>Abstract</p> <p>Background</p> <p>As part of the NHLBI Family Blood Pressure Program, the Genetic Epidemiology Network of Arteriopathy (GENOA) recruited 575 sibships (n = 1583 individuals) from Rochester, MN who had at least two hypertensive siblings diagnosed before age 60. Linkage analysis identified a region on chromosome 2 that was investigated using 70 single nucleotide polymorphisms (SNPs) typed in 7 positional candidate genes, including adducin 2 (<it>ADD2</it>).</p> <p>Method</p> <p>To investigate whether blood pressure (BP) levels in these hypertensives (n = 1133) were influenced by gene-by-drug interactions, we used cross-validation statistical methods (i.e., estimating a model for predicting BP levels in one subgroup and testing it in a different subgroup). These methods greatly reduced the chance of false positive findings.</p> <p>Results</p> <p>Eight SNPs in <it>ADD2 </it>were significantly associated with systolic BP in untreated hypertensives (p-value < 0.05). Moreover, we also identified SNPs associated with gene-by-drug interactions on systolic BP in drug-treated hypertensives. The TT genotype at SNP rs1541582 was associated with an average systolic BP of 133 mmHg in the beta-blocker subgroup and 148 mmHg in the diuretic subgroup after adjusting for overall mean differences among drug classes.</p> <p>Conclusion</p> <p>Our findings suggest that hypertension candidate gene variation may influence BP responses to specific antihypertensive drug therapies and measurement of genetic variation may assist in identifying subgroups of hypertensive patients who will benefit most from particular antihypertensive drug therapies.</p